Endocrine Abstracts

Introduction: The development of malignancies in patients with Primary Hyperparathyroidism (PHP) occurs in the context of Multiple Endocrine Neoplasia (MEN) Syndrome. The association of PTH levels with cancer in patients with sporadic PHP has not been clarified. The aim of this study was to investigate whether PTH levels are related to the presence of thyroid cancer (TH) or other types of cancer in patients with PHP.Methods: We included patients with bio...

Introduction: Previous studies have shown that the G691S and S904S variants of RET proto-oncogene are associated with Multiple Endocrine Neoplasia (MEN) 2A syndrome and have a modifier effect on the age of onset. They are also associated with Papillary Thyroid Carcinoma and with Pheochromocytoma without Medullary Thyroid Carcinoma (MTC). Nevertheless, the influence of these polymorphisms on cases of sporadic MTC is still unclear. We present a patient with sporadic Med...

Introduction: Most thyroid neoplasms arise from follicular cells and are well differentiated. We present an interesting case of a rare first manifestation of Papillary Thyroid Carcinoma (PTC) as a cervical cystic mass, as well as the therapeutic approach.Material-method: A 29 year-old-male, without personal or family history for PTC and no history of neck radiation referred to our department because of a slow growing right lateral cervical mass in the la...

Introduction: TSI (Thyroid Stimulating Immunoglobulin) antibodies are a form of immunoglobulin G (IgG) that can bind to thyrotropin receptors on the thyroid gland causing over-production of thyroid hormones and hyperthyroidism. The presence of positive TSI is considered pathognomonic for Graves’ disease. Although the association between Graves’ disease and thyroid cancer (TC) has been reported in previous studies, the association between the levels of TSI antibodies ...